Despite the high sensitivity of the DNAzymes among other diagnostic constructs, it's still not satisfying for the viral diagnosis due to the insufficient LOD. In this study, we discuss a developed DNAzyme-based machine with LOD 0.1 pM. In a trial to enable competition with the RT-qPCR.

Эльдиб А.А., Рубель М.С., Заблоцкая С.С. (науч. рук. Колпащиков Д.М.) DNA Machine for SARS-COV-2 Detection in the Clinical Samples // Сборник тезисов докладов конгресса молодых ученых. Электронное издание. – СПб: Университет ИТМО, [2021]. URL: https://kmu.itmo.ru/digests/article/5344