In this study, we develop antisense oligonucleotide-releasing cassettes (ASO-RCs) for cancer treatment. The ASO-RCs were designed and assembled for cancer marker-dependent release of an antisense agent followed by the selective cleavage of the targeted mRNA.
Анвар М., Эльдиб А.А., Дрозд В.С. (науч. рук. Колпащиков Д.М.) MARKER INDUCED CLEAVAGE OF A TARGETED mRNA USING THE ANTISENSE OLIGONUCLEOTIDE-RELEASING CASSETTE (ASO-RC) // Сборник тезисов докладов конгресса молодых ученых. Электронное издание. – СПб: Университет ИТМО, [2022]. URL: https://kmu.itmo.ru/digests/article/9570