In the biomedical fields, hydrogels play a crucial role for treating damaged tissues and organs. Hydrogels made of natural polymers have gained tremendous attention as effective biomaterials due to their potential for regeneration of many tissues in the human body. But their use is restricted in clinical applications due to their poor mechanical stability and degradability. Hence, specific chemical modifications have been employed to enhance the mechanical, degradable and adhesive properties of the polymer, by covalently crosslinking the polymer using nontoxic crosslinkers. [1,2]. These hydrogels are synthesized by crosslinking oxidized pullulan with chitosan, resulting in high water content that allows them to absorb and retain large volumes of fluids, which promotes wound repair.
Элангвэ К. (науч. рук. Успенская М.В.) INFLUENCE OF OXIDIZED PULLULAN CONCENTRATION ON THE PHYSICAL PROPERTIES OF CHITOSAN BASED HYDROGELS FOR BIOMEDICAL APPLICATIONS // Сборник тезисов докладов конгресса молодых ученых. Электронное издание. – СПб: Университет ИТМО, [2024]. URL: https://kmu.itmo.ru/digests/article/11884