Since the golden age of antibiotics, scientists have long been on the search for better antifungal compounds so that immunocompromised patients would have a better quality of life. This search has led us to sources of antifungal compounds from natural sources. Actinobacteria associated with crustaceans (amphipods) and gastropods have been found to produce antifungal molecules to help their hosts fight against pathogenic fungi. In this study, Micromonospora and Saccharopolyspora were obtained from Ommatogammarus sp. and Benedictia sp. respectively. We found that extracts from Micromonospora and Saccharopolyspora have proven to possess compounds that inhibit the growth of C. albicans. This study confirmed that Invertebrates from Lake Baikal are a promising source of bioactive compounds.
Чимезие К., Цветикова С.А., Герман В.В. (науч. рук. Кошель Е.И.) Antifungal activity of extracts of Saccharopolyspora and Micromonospora from Invertebrates in Lake Baikal // Сборник тезисов докладов конгресса молодых ученых. Электронное издание. – СПб: Университет ИТМО, [2023]. URL: https://kmu.itmo.ru/digests/article/11690